|
KMID : 0359920060250050835
|
|
Korean Journal of Nephrology
2006 Volume.25 No. 5 p.835 ~ p.839
|
|
|
A Case of Neuroleptic Malignant Syndrome (NMS) with Myoglobulinemic Acute Renal Failure and Lithium Intoxication due to Lithium-olanzapine Combination
|
|
Oh Won-Taek
Maeng Chi-Hoon
Park Mi-Na
Choi Sun-Young
Chung Kyung-Hwan
Moon Ju-Young
Lee Tae-Won
Ihm Chun-Gyoo
Lee Sang-Ho
|
|
|
Abstract
|
|
|
|
We report a patient developed neuroleptic malignant syndrome (NMS) with myoglobulinemic acute renal failure and lithium intoxication due to lithiumolanzapine combination, who was successfully treated by hemodiafiltration. A 34-year-old woman with a 14-year history of bipolar disorder had been treated with lithium-olanzapine during last four days. She was admitted to our hospital for muscular rigidity, hyperthermia and altered consciousness. On admission, rhabdomyolsis was demonstratd by biochemical methods and serum level of lithium was 3.78 mEq/L which was far above toxic level. After the diagnosis of NMS with acute renal failure and lithium intoxication, olanzapine and lithium were discontinued and conservative measures and continuous venovenous hemodiafiltration were instituted. She recovered without any neurologic sequelae. (Korean J Nephrol 2006;25(5):835-839)
|
|
|
KEYWORD
|
|
|
Neuroleptic malignant syndrome, NMS, Acute renal failure, Lithium intoxication
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|